The antimicrobial peptide Microcin C7 inhibits the growth of <i>Porphyromonas gingivalis</i> and improves the periodontal status in a rat model
Microcin C7 demonstrated favorable biocompatibility, antibacterial activity, and anti-inflammatory effect, and could decrease the alveolar bone resorption in a rat model, indicating the promising potential for clinical translation and application on P. gingivalis-associated diseases.
Authors
- Na Liu (ORCID: https://orcid.org/0009-0009-2294-2350)
- Qianqian Zhang (ORCID: https://orcid.org/0000-0003-1569-0350)
- Yue Chen (ORCID: https://orcid.org/0009-0004-5110-6400)
- Sijia Zhang (ORCID: https://orcid.org/0000-0002-1510-0720)
- Shuo Zhou (ORCID: https://orcid.org/0000-0003-2795-6865)
- Di Miao
- Jinyang Li (ORCID: https://orcid.org/0000-0001-7003-2153)
Institutions
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1093/jambio/lxae247
- Citations
- 2
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.69