Frequency of <i>CD40</i>‐1C>T polymorphism (rs1883832) and association with response to treatment in children with primary immune thrombocytopenia
CD40 rs1883832 polymorphism may contribute to predisposition and response to upfront corticosteroids therapy of pediatric pITP. These findings improve our understanding of the compound pathophysiology of ITP, suggest important clinical potentials, and open the door for further research on the mechanistic role of CD40 rs1883832 in ITP development and progression.
Authors
- Mustafa Adel Younis
- Elsayed Abdelkreem (ORCID: https://orcid.org/0000-0002-8976-2989)
- Elham O. Hamed (ORCID: https://orcid.org/0000-0003-4093-6092)
- Heba A. Ahmed (ORCID: https://orcid.org/0000-0002-5680-8610)
- Nagwa M. Abo Elmahassen
Institutions
- University of Ha'il (SA)
- Ministry of Health (SA)
- Sohag University (EG)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1002/pbc.31356
- Citations
- 3
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.36