Brain Functional Alterations in Patients With Benign Paroxysmal Positional Vertigo Demonstrate the Visual–Vestibular Interaction and Integration
The spontaneous activity of certain brain regions in the bilateral occipital and frontoparietal lobes of patients with BPPV was reduced, whereas the activity in the cerebellar vermis was increased. Additionally, there were reductions in FC between the precuneus and occipital cortex or paracentral lobule, as well as within the occipital cortex. The functional alterations in these brain regions may be associated with the inhibitory interaction and functional integration of visual, vestibular, and sensorimotor systems. The functional alterations observed in the visual cortex and precuneus may represent adaptive responses associated with residual dizziness.
Authors
- Xiaoxia Du (ORCID: https://orcid.org/0000-0001-8470-7852)
- Guo-hong Cui (ORCID: https://orcid.org/0009-0002-2736-9847)
- Xuhong Sun
- Jian‐Ren Liu (ORCID: https://orcid.org/0000-0002-2319-7788)
- Wei Chen
- Liang Shu (ORCID: https://orcid.org/0000-0003-0948-4681)
- Hui Pan (ORCID: https://orcid.org/0009-0007-3627-4336)
- Jing Wu (ORCID: https://orcid.org/0000-0002-5507-3384)
- Chen‐Yan Zhou
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai University of Sport (CN)
- Shanghai Ninth People's Hospital (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1002/brb3.70053
- Citations
- 1
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- Shanghai Municipal Education Commission
- Science and Technology Commission of Shanghai Municipality
- Shanghai Jiao Tong University
- School of Medicine, Shanghai Jiao Tong University