Trem2 acts as a non‐classical receptor of interleukin‐4 to promote diabetic wound healing

These analyses offer novel insight into the role of IL-4/Trem2 signalling as a mediator of myeloid cell-fibroblast crosstalk that may represent a viable therapeutic target for efforts to enhance diabetic wound healing.

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Publication Details

Journal
Clinical and Translational Medicine
Published
2024-09-30
DOI
https://doi.org/10.1002/ctm2.70026
Citations
9
Primary Topic
Wound Healing and Treatments
Type
article
Field-Weighted Citation Impact
2.25

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article

Trem2 acts as a non‐classical receptor of interleukin‐4 to promote diabetic wound healing

Qian Wu, Wanqing Liao, Chao Zhang, Weiwei Jiang et al.
9 citations
Clinical and Translational Medicine
Wound Healing and Treatments
2.25
article

Trem2 acts as a non‐classical receptor of interleukin‐4 to promote diabetic wound healing

Qian Wu, Wanqing Liao, Chao Zhang, Weiwei Jiang, Mingwei Du, Xinlin Zhu, Juan Chen, Keming Zhang, Weihua Pan, Youming Chen, Wenjie Fang, Zhaoxiang Zeng
article en
9 citations

Abstract

These analyses offer novel insight into the role of IL-4/Trem2 signalling as a mediator of myeloid cell-fibroblast crosstalk that may represent a viable therapeutic target for efforts to enhance diabetic wound healing.

Clinical and Translational MedicineVol. 14(10)
Shanghai Jiao Tong University (CN), Shanghai Changzheng Hospital (CN), Shanghai Public Health Clinical Center (CN), Tongren Hospital (CN), Shanghai First People's Hospital (CN)
National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality
Good health and well-being
Openalex Percentile: Top 11%
Wound Healing and Treatments
2.25
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