Practical Copper‐Catalyzed Double <scp><i>N</i></scp>‐Arylation of Cyclic Diaryliodoniums: Synthesis of <scp>5<i>H</i></scp>‐Dibenzo[<scp><i>d, f</i></scp>][<scp><i>1,3</i></scp>]Diazepine, and Benzo[<scp><i>c</i></scp>]Cinnoline Derivatives
ABSTRACT An efficient access to novel families of 7‐membered dibenzodiazepines and 6‐membered benzo[ c ]cinnoline derivatives has been elaborated. The synthetic strategy is based on a copper‐catalyzed double N ‐arylation of cyclic diaryliodoniums with imidamides and 4‐substituted 1, 2, 4‐triazoline‐3, 5‐diones (TADs) respectively under ambient reaction conditions. A mechanistic rationale for the double N ‐arylation is discussed.
Authors
- Yujuan Wu
- Lianji Zhang
- Yuhui Zhao (ORCID: https://orcid.org/0000-0003-0937-1898)
- Wanguo Wei (ORCID: https://orcid.org/0000-0002-2429-8281)
- Zhiqiang Zhang (ORCID: https://orcid.org/0000-0002-9959-4106)
- Cuiping Wang (ORCID: https://orcid.org/0000-0002-7108-7516)
Institutions
- University of Science and Technology Liaoning (CN)
Publication Details
- Journal
- Journal of Heterocyclic Chemistry
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1002/jhet.4914
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- National Natural Science Foundation of China