Neuroimmune Interactions in Stress and Depression: Exploring the Molecular and Cellular Mechanisms within the Neuroinflammation-depression Nexus

The NIIS model views depression as the terminal stage of chronic stress, pathogenetically linked to latent neuroinflammation. This insight not only advances our understanding of their etiopathogenesis but also paves the way for developing precise therapeutic interventions.

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Publication Details

Journal
Current Medicinal Chemistry
Published
2024-09-30
DOI
https://doi.org/10.2174/0109298673320710240920055041
Citations
5
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.79
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article

Neuroimmune Interactions in Stress and Depression: Exploring the Molecular and Cellular Mechanisms within the Neuroinflammation-depression Nexus

Desheng Hu, Alexey Sarapultsev, Maria Komelkova, Evgeni Gusev et al.
5 citations
Current Medicinal Chemistry
Tryptophan and brain disorders
0.79
article

Neuroimmune Interactions in Stress and Depression: Exploring the Molecular and Cellular Mechanisms within the Neuroinflammation-depression Nexus

Desheng Hu, Alexey Sarapultsev, Maria Komelkova, Evgeni Gusev, В. А. Черешнев
article en
5 citations

Abstract

The NIIS model views depression as the terminal stage of chronic stress, pathogenetically linked to latent neuroinflammation. This insight not only advances our understanding of their etiopathogenesis but also paves the way for developing precise therapeutic interventions.

Current Medicinal ChemistryVol. 31
South Ural State University (RU), Institute of Immunology and Physiology (RU), Union Hospital (CN), Huazhong University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 33%
Tryptophan and brain disorders
0.79
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