Hemolytic anemia in childhood secondary to Mycoplasma Pneumoniae pneumonia

Autoimmune hemolytic anemia is rare in childhood with an incidence of approximately 0.8-1.25 cases per 100,000 children and is the most frequent cause of extracorpuscular hemolytic anemia, having a higher incidence between 3 and 4 years of age. Most of them are idiopathic, although they can also be secondary to autoimmune diseases, lymphoproliferative syndromes, tumors or infections (notably Mycoplasma and Epstein-Barr). They usually present as a self-limiting condition associated with a viral infection. Children under 2 years of age and adolescents frequently present chronic forms, associated or not, with systemic diseases, especially immunodeficiencies or autoimmune disorders. We present the case of an 11-year-old male patient, diagnosed with pneumonia with positive serologies for Mycoplasma and Cytomegalovirus, who developed autoimmune hemolytic anemia and required blood transfusion.

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Published
2024-09-27
DOI
https://doi.org/10.60147/b8a0cabd
Primary Topic
Blood groups and transfusion
Type
article
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article

Hemolytic anemia in childhood secondary to Mycoplasma Pneumoniae pneumonia

M.a Mercedes Santos
Blood groups and transfusion
article

Hemolytic anemia in childhood secondary to Mycoplasma Pneumoniae pneumonia

M.a Mercedes Santos
article en

Abstract

Autoimmune hemolytic anemia is rare in childhood with an incidence of approximately 0.8-1.25 cases per 100,000 children and is the most frequent cause of extracorpuscular hemolytic anemia, having a higher incidence between 3 and 4 years of age. Most of them are idiopathic, although they can also be secondary to autoimmune diseases, lymphoproliferative syndromes, tumors or infections (notably Mycoplasma and Epstein-Barr). They usually present as a self-limiting condition associated with a viral infection. Children under 2 years of age and adolescents frequently present chronic forms, associated or not, with systemic diseases, especially immunodeficiencies or autoimmune disorders. We present the case of an 11-year-old male patient, diagnosed with pneumonia with positive serologies for Mycoplasma and Cytomegalovirus, who developed autoimmune hemolytic anemia and required blood transfusion.

Vol. 26(103)
PepsiCo (United Kingdom) (GB)
Openalex Percentile: Top 72%
Blood groups and transfusion
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