Hepatitis B virus (HBV) viremia despite tenofovir disoproxil fumarate-containing antiretroviral therapy in persons with HBV/HIV coinfection
HBV viremia despite high adherence to TDF/3TC-based ART may be associated with the presence of TFV RAMs. These findings highlight the need for enhanced resistance monitoring and further research to examine the clinical significance of reported TFV RAMs. Individuals with HBV/HIV coinfection and TFV resistance on TDF-based ART may need alternative treatment strategies.
Authors
- Isaac Boamah (ORCID: https://orcid.org/0000-0003-4403-5558)
- Elizabeth Odegard
- Adjoa Obo-Akwa
- Hongmei Yang (ORCID: https://orcid.org/0000-0003-0924-5795)
- Awewura Kwara (ORCID: https://orcid.org/0000-0002-1118-8331)
- Jason T. Blackard (ORCID: https://orcid.org/0000-0003-2876-3811)
- Margaret Lartey
- Peter L. Anderson (ORCID: https://orcid.org/0000-0002-1200-8494)
- Oluwayemisi Ojewale
- Heidi L. Meeds (ORCID: https://orcid.org/0009-0001-3123-135X)
- Patrick B. Ryan (ORCID: https://orcid.org/0000-0002-9727-2138)
- Kenneth Tachi (ORCID: https://orcid.org/0000-0002-0065-7139)
- Vincent Ganu (ORCID: https://orcid.org/0000-0001-8649-4344)
- K. Antwi
Institutions
- University of Ghana (GH)
- University of Health and Allied Sciences (GH)
- Korle Bu Teaching Hospital (GH)
- University of Florida (US)
- North Florida/South Georgia Veterans Health System (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Rochester (US)
- University of Montana (US)
- University of Cincinnati Medical Center (US)
- Florida College (US)
Publication Details
- Journal
- Journal of Clinical Virology
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1016/j.jcv.2024.105733
- Citations
- 5
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.93
Funders
- University of Florida
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases