Efficacy and Safety of First-Line Palliative Chemotherapy with Fluorouracil Plus Leucovorin, Oxaliplatin, and Docetaxel (FLOT) in HER2-Negative Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma: A Single-Institutional Real-World Experien
In the present study, biweekly FLOT regimen with primary prophylactic granulocyte colony-stimulating factor demonstrated encouraging efficacy with a favorable nongastrointestinal toxicity profile in Indian patients with HER2-negative metastatic gastric or GEJ adenocarcinoma. Clearly, this well-tolerated triplet regimen should be explored further through large prospective randomized trials in Asian patients.
Authors
- Amitabh Kumar Upadhyay (ORCID: https://orcid.org/0000-0002-3779-7645)
- Vanita Pandey (ORCID: https://orcid.org/0000-0002-1286-1110)
- Jaishree Bankira
- Sujata Mitra
- Subhrojyoti Mukherjee
- Rahul Panda
- Tamojit Chaudhuri
Institutions
- Tata Memorial Hospital (IN)
- Tata Main Hospital (IN)
- Manipal-Tata Medical College, Jamshedpur
Publication Details
- Journal
- South Asian Journal of Cancer
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1055/s-0044-1791524
- Citations
- 1
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.42