Ficolin-3 induces apoptosis and suppresses malignant property of hepatocellular carcinoma cells via the complement pathway
FCN3 has a malignant suppressor role in HCC cells. Our study provides new insights into the molecular mechanisms that drive HCC progression and potential therapeutic targets for treating HCC.
Authors
- Ruolei Hu
- Yu‐Chiao Chiu (ORCID: https://orcid.org/0000-0003-1647-8634)
- Andrew P. Hinck (ORCID: https://orcid.org/0000-0003-3320-8054)
- Lu‐Zhe Sun (ORCID: https://orcid.org/0000-0001-7117-4559)
- Francisco Cigarroa (ORCID: https://orcid.org/0000-0002-7432-8880)
- Łukasz Wieteska (ORCID: https://orcid.org/0000-0002-5890-6513)
- Guixi Zheng (ORCID: https://orcid.org/0000-0003-2856-9592)
- Acarizia Easley
- Hakim Bouamar (ORCID: https://orcid.org/0009-0006-9627-1877)
- Carla R. Zeballos Torrez
- Yidong Chen (ORCID: https://orcid.org/0000-0001-6806-2185)
- Lian‐Qiu Wu
- Cinthia S Hinck
- Mátyás Cserháti (ORCID: https://orcid.org/0000-0002-3673-9152)
Institutions
- The University of Texas at San Antonio Health Science Center (US)
- University of Pittsburgh (US)
- Children's Cancer Center (US)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Life Sciences
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1016/j.lfs.2024.123103
- Citations
- 5
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.20