38 Assessment of device-measured physical activity and associated clinical outcomes in cardiac rehabilitation using a novel statistical tool

<h3>Background</h3> Physical activity (PA) is a cornerstone of Cardiac Rehabilitation (CR) and is vital for improving health outcomes, including cardiorespiratory fitness (CRF). Wearable devices can be used to obtain objective PA data but, currently, statistical tools to examine and understand longitudinal PA data during CR are lacking. <h3>Aim</h3> To apply novel statistical tools to assess device-based PA data and better infer associated clinical outcomes during CR. <h3>Methods</h3> This secondary analysis used device-measured PA data from a recent digital CR randomised controlled trial (RCT) that increased CRF by 2-fold compared to usual CR alone. In this RCT, 130 patients were randomised to either an intervention group (N=65) or control group (N=65). All patients wore a wrist-mounted accelerometer for 8 weeks and the number of minutes spent in differing PA intensities at an hourly resolution was analysed. Patients were excluded who had &gt;5 incomplete days, resulting in a sample of 53 patients (control N=31; intervention N=22). A day was considered complete if the accelerometer was worn for ≥80% of the waking day. PA data was assessed using the Trend Locally Stationary Wavelet (TLSW) model. <h3>Results</h3> Sedentary time was elected as the PA outcome of interest. In figure 1, intervals where the confidence bands do not overlap indicate where sedentary time was statistically significantly different between groups. The novel TLSW tool successfully characterised the intervention response, indicating that the intervention group spent 41% of the intervention period (equivalent to 26 days) engaged in statistically significantly lower sedentary time than controls. <h3>Conclusion</h3> The application of a novel TLSW tool to assess device-measured PA enhances understanding of PA behaviour change during CR and has highlighted the significant importance of reducing sedentary time for improving CRF. This presents new opportunities to optimise CR outcomes by harnessing everyday PA at all intensities, to deliver more personalised care.