Multisite DNA methylation alterations of peripheral blood mononuclear cells serve as novel biomarkers for the diagnosis of AIS/stage I lung adenocarcinoma: a multicenter cohort study
The novel developed LDP score represented a convenient and effective assay for the detection of AIS/stage I LUAD with high sensitivity and specificity, and had demonstrated unique advantages over traditional detection methods.
Authors
- Huiting Xu (ORCID: https://orcid.org/0009-0003-8314-9475)
- Xiaoyi He
- Shibiao Liu (ORCID: https://orcid.org/0000-0002-4945-8093)
- Qiuchen Qi (ORCID: https://orcid.org/0000-0003-4329-3723)
- Peilong Li (ORCID: https://orcid.org/0000-0002-7441-6514)
- Shijun Li (ORCID: https://orcid.org/0000-0002-1503-5770)
- G. Li (ORCID: https://orcid.org/0009-0005-4924-2195)
- Yan Xie (ORCID: https://orcid.org/0000-0001-8987-4844)
- Shujun Zhang (ORCID: https://orcid.org/0009-0004-4335-050X)
- Fang Wang (ORCID: https://orcid.org/0000-0001-6489-4507)
- Jianping Li (ORCID: https://orcid.org/0000-0002-4859-1677)
- Yi Zhang (ORCID: https://orcid.org/0000-0002-0440-1798)
- Juan Li (ORCID: https://orcid.org/0000-0003-0905-7188)
- Suli Yang
- Tiantian Wang (ORCID: https://orcid.org/0000-0003-2358-9893)
- Guotao Yin
- Mengqiu Xiong
- Chuanxin Wang (ORCID: https://orcid.org/0000-0002-3796-6293)
- Yongcai Zhu
- Lutao Du (ORCID: https://orcid.org/0000-0002-3796-6293)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Qilu University of Technology (CN)
- Dalian Medical University (CN)
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Second Hospital of Shandong University (CN)
- Nantong Tumor Hospital (CN)
- Shandong Provincial Hospital (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Shanghai Clinical Research Center (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
- Qilu Hospital of Shandong University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1097/js9.0000000000002101
- Citations
- 6
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Shandong University
- National Natural Science Foundation of China
- Key Technology Research and Development Program of Shandong
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities