SMART Medical Review: Acute Pancreatitis Assessment and Management in the First 24 Hours
Acute pancreatitis (AP) is an inflammatory reaction of the pancreas caused by inappropriate trypsin activation and an injury / innate inflammatory response. The many etiologies and potentially life-threatening consequences of AP require that clinicians initiate prompt and individualized treatment upon diagnosis. Application of new advances in the management of AP are required at the point of care. To facilitate care, a group of clinical experts have developed a set of recommendations for the evaluation and management of AP during the first 24 hours based on current evidence and evolving concepts. Ten areas of care are addressed where expert recommendations may be useful: (1) physical examination, (2) laboratory tests, (3) diagnosis, (4) early treatment, (5) severity determination, (6) etiology-based management, (7) typical orders sets, (8) determining of appropriate level of care, (9) quality of care, and (10) quality improvement recommendations. Conclusion: These recommendations should become available as clinical decision support tools that are accessible at the point of care, in real time.
Authors
- Thiruvengadam Muniraj (ORCID: https://orcid.org/0000-0002-4904-2645)
- Vivek Kaul (ORCID: https://orcid.org/0000-0002-7978-7517)
- Nalini M. Guda (ORCID: https://orcid.org/0000-0001-9357-174X)
- Daniel M. Spagnolo
- David C. Whitcomb (ORCID: https://orcid.org/0000-0002-4462-1410)
- Shrinivas Bishu (ORCID: https://orcid.org/0000-0003-4823-5805)
- Daniel S. Strand (ORCID: https://orcid.org/0000-0001-5573-6291)
- Georgios I. Papachristou (ORCID: https://orcid.org/0000-0001-9915-703X)
- Cameron R. Breze (ORCID: https://orcid.org/0000-0003-1132-5655)
- Beth Schrope (ORCID: https://orcid.org/0000-0003-0313-8120)
- Amitabh Chak (ORCID: https://orcid.org/0000-0002-0021-7862)
- Timothy Gardner
- Jason R. Taylor (ORCID: https://orcid.org/0000-0002-7871-448X)
- Peter Lee (ORCID: https://orcid.org/0000-0002-3898-8881)
- Charles Melbern Wilcox
- Paul R. Tarnasky
Institutions
- Dartmouth–Hitchcock Medical Center (US)
- Strong Memorial Hospital (US)
- Orlando Health (US)
- University of Pittsburgh (US)
- University of Michigan (US)
- University of Virginia Health System (US)
- The Ohio State University Wexner Medical Center (US)
- Yale University (US)
- Precision Therapeutics (United States) (US)
- Michigan Medicine (US)
- Aurora St. Luke's Medical Center (US)
- Methodist Dallas Medical Center (US)
- Columbia College (CA)
- Saint Louis University (US)
- The Ohio State University (US)
- Case Western Reserve University (US)
- Columbia University (US)
Publication Details
- Journal
- SMART-MD journal of precision medicine.
- Published
- 2024-09-30
- DOI
- https://doi.org/10.69734/7dcnna53
- Citations
- 1
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.57