Carotid Baroreceptor Stimulation Ameliorates Pulmonary Arterial Remodeling in Rats With Hypoxia‐Induced Pulmonary Hypertension
Our results showed that CBS could rebalance autonomic tone, inhibit pulmonary arterial remodeling, and improve pulmonary hemodynamics and right ventricle function, thus delaying hypoxia-induced pulmonary hypertension progression. There may be a reciprocal interaction between <i>POSTN</i> and <i>BDNF</i> that is responsible for the underlying mechanism.
Authors
- Ling Shu
- Mingyan Dai (ORCID: https://orcid.org/0000-0001-9145-8663)
- Xuesheng Fang
- Mingwei Bao (ORCID: https://orcid.org/0000-0002-2083-9909)
- Jing Wang (ORCID: https://orcid.org/0000-0003-0875-2453)
- Junxia Zhang (ORCID: https://orcid.org/0000-0003-1350-9001)
- Tuantuan Tan
- Jie Chen
- Zhiling Hu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1161/jaha.124.035868
- Citations
- 2
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.84