Systemic inflammation in asymptomatic hyperuricaemia with sonographic crystal deposits, including a comparison with normouricaemia and gout
Hyperuricaemia is associated with substantial inflammation and some degree of active pyroptosis. Four different ultrasound definitions for AH with MSU deposits yielded similar findings, although we noted some differences in calprotectin, CRP, and TGF-β. Sex, obesity, and comorbidities influenced some inflammatory responses.
Authors
- Mariano Andrés (ORCID: https://orcid.org/0000-0002-0219-9055)
- Miguel Perdiguero (ORCID: https://orcid.org/0000-0002-1076-6611)
- Sílvia Gómez (ORCID: https://orcid.org/0000-0002-2833-565X)
- Rocío Caño (ORCID: https://orcid.org/0000-0002-2803-4347)
- Rubén Francés (ORCID: https://orcid.org/0000-0001-5105-1201)
- Teresa Lozano (ORCID: https://orcid.org/0000-0003-4066-3573)
- María-Luisa Peral-Garrido (ORCID: https://orcid.org/0000-0001-9876-3564)
- Ruth Sánchez-Ortiga (ORCID: https://orcid.org/0000-0002-0117-960X)
- Elena Caro-Martínez (ORCID: https://orcid.org/0000-0001-8737-2234)
- Eliseo Pascual (ORCID: https://orcid.org/0000-0002-3056-4478)
- Alejandra Bermúdez-García
- Paula Boix
- C. Ruiz-García
Institutions
- Universitat de Miguel Hernández d'Elx (ES)
- University of Alicante (ES)
- Food and Nutrition Service (US)
- Primary Health Care (QA)
- Hospital Universitario del Vinalopó (ES)
- Hospital General Universitario de Alicante Doctor Balmis (ES)
- Biomedical Research Institute (US)
- Medical Research Network (US)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1093/rheumatology/keae533
- Citations
- 6
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 2.04