Fatty Liver - Insulin, Methionine, Choline, Betaine, Homocysteine, Mg, Se, Vitamin E and Pioglitazone

Fatty liver [1] is associated with cellular dysfunction, why GSH (glutathione) [2], its association with homocysteine (HCy) and methionine (Met) need closer assessment. Extreme form of dysfunction is necrosis [1]. HCy-Met cycle consist of two poles {look [3], Figure 1, text discussable}: Met (donor of methyl group) and HCy (recipient of methyl group) and circulation between them. The methylation of HCy is not the normal route of HCy [4].