Buruli ulcer: An epidemiological update from Japan
Japan is one of the rare non-tropical countries with documented cases of Buruli ulcer (BU). Mycobacterium ulcerans subsp. shinshuense has been identified as the causative agent. The first report of BU in Japan dates back to 1982, with sporadic reports thereafter. Recently, the number of cases has been on the increase, and 50 cases (57.7%) are from the past decade alone, out of a total of 87 cases reported to date. Japan's well-developed healthcare facilities play a crucial role in enabling detailed investigations and providing appropriate treatment for patients, contributing to a favorable prognosis. However, the rarity of the disease results in lack of awareness among healthcare professionals, leading to frequent delays in diagnosis. This article aims to offer an updated overview of BU cases in Japan and to raise awareness of BU among dermatologists and other healthcare professionals in a non-endemic setting.
Authors
- Rie Yotsu (ORCID: https://orcid.org/0000-0001-9102-1912)
- Toshifumi Takahashi (ORCID: https://orcid.org/0000-0001-6059-9092)
- Mariko Sugawara‐Mikami (ORCID: https://orcid.org/0000-0003-3136-8046)
- Manabu Ato (ORCID: https://orcid.org/0000-0002-3178-2645)
- Ryo Fukaura (ORCID: https://orcid.org/0000-0002-3946-7893)
- Yoshihiko Hoshino (ORCID: https://orcid.org/0000-0002-3132-0715)
- Noriki Fujimoto (ORCID: https://orcid.org/0000-0003-4051-0649)
- Norihisa Ishii (ORCID: https://orcid.org/0000-0002-1566-0031)
- Yuji Miyamoto (ORCID: https://orcid.org/0000-0003-4247-1196)
- Masashi Akiyama (ORCID: https://orcid.org/0000-0001-5863-9315)
- Chiaki Murase
Institutions
- Tulane University (US)
- Shiga University of Medical Science (JP)
- Zen-Noh (Japan) (JP)
- National Institute of Infectious Diseases (JP)
- Miwa Internal Medicine Clinic (JP)
- National Center for Global Health and Medicine (JP)
- Nagasaki University (JP)
- Nagoya University (JP)
Publication Details
- Journal
- The Journal of Dermatology
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1111/1346-8138.17483
- Citations
- 3
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Japan Agency for Medical Research and Development
- Japan International Cooperation Agency
- Japan Society for the Promotion of Science