Targeting Kidney Inflammation After Brain Death and Cold Storage: Investigating the Potential of an NLRP3 Inflammasome Inhibitor (MCC950) for Preconditioning Donor Kidneys
These findings suggest that MCC950 treatment holds promise for mitigating the proinflammatory state observed in kidneys after BD and CS.
Authors
- Mário Abbud‐Filho (ORCID: https://orcid.org/0000-0002-5079-9813)
- Cristiano de Jesus Correia (ORCID: https://orcid.org/0000-0002-1690-9951)
- Ana Cristina Breithaupt‐Faloppa (ORCID: https://orcid.org/0000-0003-0554-0674)
- Heloisa Cristina Caldas (ORCID: https://orcid.org/0000-0002-8303-3929)
- Luíz Felipe Pinho Moreira (ORCID: https://orcid.org/0000-0003-0179-4976)
- Naiane do Nascimento Gonçalves
- Ludimila Leite Marzochi (ORCID: https://orcid.org/0000-0002-2835-5562)
- Maria Alice Sperto Ferreira Baptista (ORCID: https://orcid.org/0000-0003-0714-2012)
Institutions
- Faculdade de Medicina de São José do Rio Preto (BR)
- Hospital de Base (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Instituto do Coração (PT)
Publication Details
- Journal
- Transplantation
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1097/tp.0000000000005211
- Citations
- 1
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 0.23