The role of glycemic traits in the mediation of the causal effect of hypothyroidism on coronary heart disease
The results of our study indicate a causal relationship between hypothyroidism and coronary heart disease. Furthermore, HbA1c partially mediated the causal effect of hypothyroidism on coronary heart disease. Consequently, intervention in this factor may reduce the risk of coronary heart disease associated with hypothyroidism.
Authors
- Yijie Li (ORCID: https://orcid.org/0000-0001-7551-117X)
- Guorong Li (ORCID: https://orcid.org/0000-0002-9439-4754)
- Yunfei Yu
- Wangfang Yang
- Zekuan Xue
- Zhiwei Jin
- Jixue Hou
Institutions
- Shihezi University (CN)
- Shandong University (CN)
- First Affiliated Hospital of Shihezi University Medical College (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-09-30
- DOI
- https://doi.org/10.3389/fendo.2024.1436713
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00