Cardiovascular magnetic resonance insights into anomalies of the mitral valve apparatus in Fabry cardiomyopathy and hypertrophic cardiomyopathy
we report greater PMs hypertrophy in FDc and a higher prevalence of PMs positional alterations (anterior and apical displacement) and myocardial crypts in HCM. All these AMVA became more pronounced with the progression of the FDc phenotype. We suggest the systematic inclusion of the analysis of AMVA by simple linear measurements on cine images in the CMR assessment of hypertrophic cardiomyopathies, to help in the differential diagnosis between HCM and FDc and to facilitate early detection of cardiac involvement in FDc.
Authors
- Lara Tondi (ORCID: https://orcid.org/0000-0001-7140-0341)
- Pietro Spagnolo (ORCID: https://orcid.org/0000-0003-0914-314X)
- Andrea F. Attanasio (ORCID: https://orcid.org/0000-0002-8007-2324)
- Giandomenico Disabato (ORCID: https://orcid.org/0000-0003-1024-1644)
- Antonia Camporeale (ORCID: https://orcid.org/0000-0001-7604-0496)
- Massimo Lombardi (ORCID: https://orcid.org/0000-0003-1700-8749)
- Federico Pieruzzi (ORCID: https://orcid.org/0000-0002-1302-6846)
- Gianpaolo Carrafiello (ORCID: https://orcid.org/0000-0002-8002-4277)
- Marco Canepa (ORCID: https://orcid.org/0000-0001-9063-5576)
- Massimo Piepoli (ORCID: https://orcid.org/0000-0003-1124-234X)
- Giada De Angeli (ORCID: https://orcid.org/0000-0003-2826-0181)
- Gianluigi Guida (ORCID: https://orcid.org/0009-0003-5666-8368)
- Paolo Fabio D’Andria
Institutions
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Ospedale Maggiore (IT)
- IRCCS Policlinico San Donato (IT)
- Azienda Ospedaliera San Gerardo (IT)
- Ospedale Policlinico San Martino (IT)
- University of Milano-Bicocca (IT)
- University of Genoa (IT)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2024-09-30
- DOI
- https://doi.org/10.3389/fcvm.2024.1458705
- Citations
- 1
- Primary Topic
- Lysosomal Storage Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.33