Association of alcohol with lung cancer risk in men with different growth hormone receptor genotypes
In men with the GHR-AA genotype, alcohol drinking at a low dose poses significantly less risk of LC compared with non-drinkers and higher alcohol consumption., the overall relationship being U-shaped. In contrast, in GHR minor allele carriers, alcohol posed a progressively greater risk of LC as amount consumed increased.
Authors
- Brian J. Morris (ORCID: https://orcid.org/0000-0003-2468-3566)
- Bradley J. Willcox (ORCID: https://orcid.org/0000-0001-9890-3520)
- Kamal Masaki (ORCID: https://orcid.org/0000-0003-1170-3118)
- Timothy A. Donlon (ORCID: https://orcid.org/0000-0001-6545-6533)
- Randi Chen (ORCID: https://orcid.org/0000-0003-3747-7964)
- Richard Allsopp (ORCID: https://orcid.org/0000-0001-7565-5325)
Institutions
- Kuakini Medical Center (US)
- University of Hawaii System (US)
Publication Details
- Journal
- Lung Cancer
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1016/j.lungcan.2024.107971
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Heart, Lung, and Blood Institute
- Division of Cancer Epidemiology and Genetics, National Cancer Institute