Danggui Shaoyao San Alleviates Early Cognitive Impairment in Alzheimer's Disease Mice Through IRS1/GSK3β/Wnt3a‐β‐Catenin Pathway
Our findings suggest that DSS potentially confers cognitive protection by alleviating central hypoglycemia through the IRS1/GSK3β/Wnt3a-β-catenin pathway. This may serve as a promising therapeutic avenue for AD.
Authors
- Ya‐Han Wang
- Ning Sheng (ORCID: https://orcid.org/0000-0002-3308-3960)
- Jiwei Zhang (ORCID: https://orcid.org/0000-0002-3826-7611)
- Kaixin Zhang (ORCID: https://orcid.org/0009-0006-9517-2885)
- Xiangqing Xu (ORCID: https://orcid.org/0000-0001-6214-2598)
- Peng‐Li Ding
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Beijing University of Chinese Medicine (CN)
- Zaozhuang Municipal Hospital (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1002/brb3.70056
- Citations
- 6
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.96
Funders
- Shandong University
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province