Mendelian Randomization Study Supports Genetic Liability to Obsessive–Compulsive Disorder Associated With the Risk of Alzheimer's Disease
This comprehensive MR study suggests that genetic liability to OCD is a causal risk factor for AD. Early intervention in patients with OCD may be beneficial in preventing future AD progression.
Authors
- Chao Fang (ORCID: https://orcid.org/0000-0001-9898-4893)
- Youjie Zeng (ORCID: https://orcid.org/0000-0003-3842-1815)
- Si Cao
- Xiaoyi Zhang (ORCID: https://orcid.org/0000-0002-4988-819X)
- Minghua Chen (ORCID: https://orcid.org/0000-0003-4525-0233)
- Nayiyuan Wu (ORCID: https://orcid.org/0000-0001-5242-3206)
- Han Su (ORCID: https://orcid.org/0000-0002-4241-4629)
Institutions
- Central South University (CN)
- Jacobi Medical Center (US)
- Hunan Cancer Hospital (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1002/brb3.70081
- Citations
- 1
- Primary Topic
- Obsessive-Compulsive Spectrum Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.64
Funders
- Natural Science Foundation of Hunan Province
- National Human Genome Research Institute