Poor compliance with germline testing recommendations in colorectal cancer patients undergoing molecular residual disease testing
Our real-world data suggest that many CRC patients receiving MRD testing and meeting NCCN (v. 2021) criteria for germline MGPT may not be receiving evaluation beyond routine MMR status. Process and educational improvements are needed in community health settings to increase access and uptake of germline testing among CRC patients regardless of age at diagnosis or MMR status.
Authors
- Suzanne Schrock-Kelley
- Youbao Sha
- Minetta C. Liu (ORCID: https://orcid.org/0000-0002-8206-5232)
- Jeffrey N. Weitzel (ORCID: https://orcid.org/0000-0001-6714-092X)
- Adam C. ElNaggar (ORCID: https://orcid.org/0000-0003-3409-583X)
- Michael J. Hall (ORCID: https://orcid.org/0000-0002-5823-6580)
- Vivienne Souter (ORCID: https://orcid.org/0000-0001-5599-8179)
- Urmi Sengupta (ORCID: https://orcid.org/0000-0002-8034-6241)
Institutions
- Fox Chase Cancer Center (US)
- Natera (United States) (US)
Publication Details
- Journal
- Communications Medicine
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1038/s43856-024-00608-6
- Citations
- 1
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.42