Phytochemical Analysis and Evaluation of Antioxidant, Antidiabetic, and Anti-inflammatory Properties of Aegle marmelos and Its Validation in an In-Vitro Cell Model
<i>A. marmelos </i>leaf<i> </i>extract was quantified to possess a substantial amount of important phytoconstituents that have promising pharmacological properties. Besides showing antidiabetic activity, the extract significantly combats the high glucose-induced ROS generation, inflammatory markers expressions, and cell migration. Further, in-depth studies and clinical trials are warranted so as to position these traditional remedies for the treatment of metabolic disorders.
Authors
- A. Rajagopal (ORCID: https://orcid.org/0009-0001-2723-518X)
- Nagaraj Manickam (ORCID: https://orcid.org/0000-0002-0049-777X)
- Viswanathan Mohan (ORCID: https://orcid.org/0000-0001-5038-6210)
- Muthuswamy Balasubramanyam (ORCID: https://orcid.org/0000-0001-9013-7024)
- S. Venkatesan (ORCID: https://orcid.org/0009-0003-5759-4217)
Institutions
- Madras Diabetes Research Foundation (IN)
- Dr. Mohan's Diabetes Specialities Centre (IN)
Publication Details
- Journal
- Cureus
- Published
- 2024-09-30
- DOI
- https://doi.org/10.7759/cureus.70491
- Citations
- 5
- Primary Topic
- Natural Antidiabetic Agents Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.79
Funders
- Science and Engineering Research Board