Phytochemical Analysis and Evaluation of Antioxidant, Antidiabetic, and Anti-inflammatory Properties of Aegle marmelos and Its Validation in an In-Vitro Cell Model

<i>A. marmelos </i>leaf<i> </i>extract was quantified to possess a substantial amount of important phytoconstituents that have promising pharmacological properties. Besides showing antidiabetic activity, the extract significantly combats the high glucose-induced ROS generation, inflammatory markers expressions, and cell migration. Further, in-depth studies and clinical trials are warranted so as to position these traditional remedies for the treatment of metabolic disorders.

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Publication Details

Journal
Cureus
Published
2024-09-30
DOI
https://doi.org/10.7759/cureus.70491
Citations
5
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
Field-Weighted Citation Impact
1.79

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article

Phytochemical Analysis and Evaluation of Antioxidant, Antidiabetic, and Anti-inflammatory Properties of Aegle marmelos and Its Validation in an In-Vitro Cell Model

A. Rajagopal, Nagaraj Manickam, Viswanathan Mohan, Muthuswamy Balasubramanyam et al.
5 citations
Cureus
Natural Antidiabetic Agents Studies
1.79
article

Phytochemical Analysis and Evaluation of Antioxidant, Antidiabetic, and Anti-inflammatory Properties of Aegle marmelos and Its Validation in an In-Vitro Cell Model

A. Rajagopal, Nagaraj Manickam, Viswanathan Mohan, Muthuswamy Balasubramanyam, S. Venkatesan
article en
5 citations

Abstract

<i>A. marmelos </i>leaf<i> </i>extract was quantified to possess a substantial amount of important phytoconstituents that have promising pharmacological properties. Besides showing antidiabetic activity, the extract significantly combats the high glucose-induced ROS generation, inflammatory markers expressions, and cell migration. Further, in-depth studies and clinical trials are warranted so as to position these traditional remedies for the treatment of metabolic disorders.

CureusVol. 16(9)
Madras Diabetes Research Foundation (IN), Dr. Mohan's Diabetes Specialities Centre (IN)
Science and Engineering Research Board
Zero hunger
Openalex Percentile: Top 13%
Natural Antidiabetic Agents Studies
1.79
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