Circulating Plasma Proteins in Aortic Stenosis: Associations With Severity, Myocardial Response, and Clinical Outcomes
Plasma proteins involved in inflammation and immune regulation were differentially expressed in patients with aortic stenosis with reduced left ventricular global longitudinal strain, and associated with adverse clinical outcomes. Their incorporation into aortic stenosis risk stratification warrants further assessment.
Authors
- Hak Chiaw Tang (ORCID: https://orcid.org/0000-0003-4096-3250)
- Poh Shuan Daniel Yeo (ORCID: https://orcid.org/0000-0002-6947-1068)
- Siew Pang Chan (ORCID: https://orcid.org/0000-0001-6239-6483)
- See Hooi Ewe (ORCID: https://orcid.org/0000-0001-8393-1772)
- Siang Chew Chai (ORCID: https://orcid.org/0000-0002-9471-6311)
- Mark Richards (ORCID: https://orcid.org/0000-0002-2023-8177)
- Y.Y. Oon (ORCID: https://orcid.org/0000-0002-7670-1810)
- James Yip (ORCID: https://orcid.org/0000-0001-5470-4554)
- Eugene S.J. Tan (ORCID: https://orcid.org/0000-0001-7273-6883)
- Evelyn Min Lee
- Jenny Chong (ORCID: https://orcid.org/0000-0002-4182-188X)
- Hean Yee Ong (ORCID: https://orcid.org/0000-0003-0566-5901)
- Calvin Chin (ORCID: https://orcid.org/0000-0002-9867-4390)
- Lee Fong Ling (ORCID: https://orcid.org/0009-0005-5203-4303)
- Wern‐Miin Soo
- Oi Wah Liew (ORCID: https://orcid.org/0000-0001-5729-2700)
- Lieng Hsi Ling (ORCID: https://orcid.org/0000-0001-6063-8530)
- Christopher R. deFilippi (ORCID: https://orcid.org/0000-0002-0660-4943)
- Lingli Gong
- Hyungwon Choi (ORCID: https://orcid.org/0000-0002-6687-3088)
- Quek Wei Yong (ORCID: https://orcid.org/0000-0003-0707-809X)
- Zee Pin Ding (ORCID: https://orcid.org/0000-0002-3349-8509)
- Josephine B. Lunaria
- Edgar Lik‐Wui Tay
- Ping Ping Goh
Institutions
- National University of Singapore (SG)
- Gleneagles Hospital (SG)
- Changi General Hospital (SG)
- Tan Tock Seng Hospital (SG)
- Khoo Teck Puat Hospital (SG)
- Sarawak Biodiversity Centre (MY)
- New Zealand Brain Research Institute (NZ)
- National University Heart Centre Singapore (SG)
- National Heart Centre Singapore (SG)
- National University Health System (SG)
- Alaska Heart and Vascular Institute (US)
- University of Otago (NZ)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1161/jaha.124.035486
- Citations
- 4
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.61