Hybrid quantification of absolute perfusion requires accurate measurement of myocardial mass

ubendocardial and transmural perfusion improve after aortic valve replacement in aortic stenosis.Accordingly, in this issue of EuroIntervention, the publication by Gallinoro et al 1 on longitudinal coronary physiology before and after transcatheter aortic valve implantation (TAVI) raises a critical point regarding the quantification of absolute myocardial perfusion.As summarised in Figure 1, we argue that the algorithm for determining absolute myocardial mass from computed tomography (CT) imaging needs validation and currently appears to be inaccurate.