Diosgenin ameliorating non‐alcoholic fatty liver disease via <scp> <i>Nrf2</i> </scp> ‐mediated regulation of oxidative stress and ferroptosis
This study highlights the potential of diosgenin from Dioscoreaceae plants in mitigating oxidative stress and ferroptosis levels through nuclear factor erythroid 2-related factor 2 regulation, offering novel insights into the treatment of non-alcoholic fatty liver disease and other metabolic disorders through traditional Chinese medicine.
Authors
- Suwen Chen (ORCID: https://orcid.org/0000-0001-9308-1564)
- Wenfei Yu (ORCID: https://orcid.org/0000-0001-9660-1684)
- Fengxia Zhang (ORCID: https://orcid.org/0000-0002-9574-8155)
- Linya Wang
- Xin Zhang (ORCID: https://orcid.org/0000-0003-4298-7926)
- Hongshuai Liu (ORCID: https://orcid.org/0000-0003-0737-6118)
- Decheng Meng
- Guoliang Yin
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Guang’anmen Hospital (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1111/dom.15945
- Citations
- 9
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.77