Clinical Evaluation of Nanohybrid Organically Modified Ceramic and Nanohybrid Conventional Bulk-fill Resin Composite in Proximal Compound Posterior Restorations: Randomized Clinical Study

Purpose: This study compared the clinical efficacy of nanohybrid organically modified ceramic (ORMOCER) bulk-fill resin composite vs nanohybrid conventional bulk-fill resin composite in proximal compound posterior restorations. Materials and methods: In this randomized controlled clinical study, a total of 30 proximal carious lesions were restored randomly with either the intervention nanohybrid ORMOCER bulk-fill resin composite (Admira Fusion X-tra) or nanohybrid conventional bulk-fill resin composite (Grandioso X-tra). Two assessors who were blinded to the study procedures evaluated restorations at baseline (1 week), 6 months, and 12 months using the World Dental Federation (FDI) criteria, measuring functional, esthetic, and biological properties. Frequency and percentage represented the categorical data. Intragroup comparisons between interventions were calculated using the Chi-squared test. Results: The overall rate of survival of nanohybrid ORMOCER bulk-fill resin composite and nanohybrid conventional bulk-fill resin composite for proximal restorations was evaluated after 1 year. No restorations failed after 12 months in biological, esthetic, and functional properties, with no statistically significant difference in intergroup or intragroup comparisons. However, the intergroup comparison between both materials showed a statistically significant difference in color match and translucency (<i>p</i> = 0.0003). Conclusion: Under the study limitations, it can be concluded that nanohybrid ORMOCER bulk-fill resin composite showed comparable clinical efficacy to the nanohybrid conventional bulk-fill resin composite. Nanohybrid ORMOCER bulk-fill resin composite demonstrated slightly superior esthetic results during the one-year follow-up. How to cite this article: Fahmy SH, El-Bialy MR, Safwat OM. Clinical Evaluation of Nanohybrid Organically Modified Ceramic and Nanohybrid Conventional Bulk-fill Resin Composite in Proximal Compound Posterior Restorations: Randomized Clinical Study. Int J Prosthodont Restor Dent 2024;14(3):146–152.