Fractionated Stereotactic Intensity-Modulated Radiotherapy for Large Brain Metastases: Comprehensive Analyses of Dose–Volume Predictors of Radiation-Induced Brain Necrosis
In five- or ten-fraction SRT, larger V55EQD2 or V60EQD2 are BN risk predictors. These biologically high doses may affect BN incidence. Thus, the planning target volume margin should be minimized as much as possible.
Authors
- Akira Torii (ORCID: https://orcid.org/0000-0003-0854-2974)
- Yuta Eguchi (ORCID: https://orcid.org/0000-0003-1212-8151)
- Taiki Takaoka (ORCID: https://orcid.org/0000-0002-2667-8923)
- Natsuo Tomita
- Nozomi Kita (ORCID: https://orcid.org/0000-0003-4183-4637)
- Akio Hiwatashi (ORCID: https://orcid.org/0000-0001-5400-5083)
- Yuki Kasai (ORCID: https://orcid.org/0000-0003-3451-0124)
- Yuta Shibamoto (ORCID: https://orcid.org/0000-0003-4255-8611)
- Taro Murai (ORCID: https://orcid.org/0000-0002-3444-2945)
- Seiya Takano (ORCID: https://orcid.org/0000-0001-6990-9923)
Institutions
- Nagoya City University (JP)
- Nagoya City University Hospital (JP)
- Shonan Kamakura General Hospital (JP)
Publication Details
- Journal
- Cancers
- Published
- 2024-09-28
- DOI
- https://doi.org/10.3390/cancers16193327
- Citations
- 2
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Japan Society for the Promotion of Science