Improved diagnostic performance of high‐sensitivity cardiac troponins in muscle dystrophies using comprehensive definition criteria for cardiac involvement: A longitudinal study on 35 patients
Elevated hs-cTnT but not hs-cTnI discriminates cardiac involvement in cases with confirmed skeletal muscle dystrophies with very high sensitivity and 100% specificity. Prior reports on worse performance may be explained by the use of less sensitive imaging methods or incomplete assessment of cardiac involvement.
Authors
- Norbert Frey (ORCID: https://orcid.org/0000-0001-7611-378X)
- Christian Salbach (ORCID: https://orcid.org/0000-0002-1799-545X)
- Barbara Ruth Milles (ORCID: https://orcid.org/0009-0004-4602-5489)
- Benjamin Meder (ORCID: https://orcid.org/0000-0003-0741-2633)
- Regina Pribe‐Wolferts
- Evangelos Giannitsis
- Tobias Täger
- Markus Weiler (ORCID: https://orcid.org/0000-0002-8942-7662)
- Christoph Reich (ORCID: https://orcid.org/0000-0002-2683-1369)
- Matthias Mueller‐Hennessen
- Mustafa Yıldırım (ORCID: https://orcid.org/0000-0001-6783-143X)
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Stanford University (US)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1111/ene.16498
- Primary Topic
- Cardiovascular Effects of Exercise
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Roche