Heptaelliptoic Acid A, a New Betulinic Acid Saponin from the Leaves of Heptapleurum ellipticum

A bstract: One new 3-O-glycoside of betulinic acid, named heptaelliptoic acid A (1), together with one known betulinic acid analogue (2), and four other compounds (3-6) were separated by combinatively chromatographic techniques.For the first time, all of the purified compounds (1-6) were reported from the H. ellipticum species.Their structures were obviously elucidated basing exhaustive and pervasive UV-VIS, FT-IR, HR-MS-ESI, and NMR experiment data.Compounds 2-4 were significantly displayed the in vitro -glucosidase inhibition (IC50 values of 11.53, 28.75, and 10.90 M, respectively) better than the acarbose positive drug (IC50 value of 214.50 M).