High fat, high sucrose diet promotes increased expression of ACE2 receptor in the SIV-infected host: implications for SARS-CoV-2 infection
The increased ACE2 receptor expression observed in lung and pancreas of SIV-infected HFSD-fed female rhesus macaques aligns with reports that diet may increase susceptibility to COVID-19. These data provide direct evidence for a link between dietary quality and cellular adaptations that may increase the risk for SARS-CoV-2 infection.
Authors
- Elizabeth Delery (ORCID: https://orcid.org/0000-0002-9759-9069)
- Danielle E. Levitt (ORCID: https://orcid.org/0000-0003-1865-1971)
- Patricia E. Molina (ORCID: https://orcid.org/0000-0002-3598-384X)
- Liz Simon (ORCID: https://orcid.org/0000-0003-4149-3406)
- Angela M. Amedee
Institutions
- Texas Tech University (US)
- Louisiana State University Health Sciences Center New Orleans (US)
- Marian University - Indiana (US)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-09-30
- DOI
- https://doi.org/10.3389/fnut.2024.1458106
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute on Alcohol Abuse and Alcoholism