FERMT1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by activating EGFR/AKT/β-catenin and EGFR/ERK pathways
FERMT1 was highly expressed in HCC and promoted viability, invasion, migration, and EMT of HCC by targeting EGFR to activate the EGFR/AKT/β-catenin and EGFR/ERK pathways. Our study revealed the role of FERMT1 in HCC and suggested that FERMT1 exerts biological effects through activating the EGFR/AKT/β-catenin and EGFR/ERK pathways.
Authors
- Sijin Yang (ORCID: https://orcid.org/0000-0002-7145-1285)
- Li Wang (ORCID: https://orcid.org/0009-0005-5697-4183)
- Mengnan Liu (ORCID: https://orcid.org/0000-0001-9991-642X)
- Jing Peng (ORCID: https://orcid.org/0000-0003-4213-7542)
- Wei Luo (ORCID: https://orcid.org/0000-0002-4472-2182)
- Xin Ma (ORCID: https://orcid.org/0000-0003-4223-1811)
- Wubin Guo
- Fei Liu (ORCID: https://orcid.org/0000-0002-9814-4226)
Institutions
- Southwest Medical University (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1016/j.tranon.2024.102144
- Citations
- 6
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 1.70