Identifying High Recurrence Risk in Breast Carcinoma Patients Through Spatial Transcriptomic Analysis
This study highlights significant differences in gene expression profiles and spatially resolved transcriptional activities between ORS-H and ORS-NH breast carcinomas. The significant up-regulation of genes and pathways associated with cell-mediated immunity, IFN response, and complement C1q in the stromal compartment of the ORS-H group warrants further evaluation with larger population cohorts.
Authors
- Jinah Chu (ORCID: https://orcid.org/0000-0001-9050-084X)
- Hyun Soo Kim (ORCID: https://orcid.org/0000-0002-2356-7822)
- Sung‐Im Do (ORCID: https://orcid.org/0000-0001-8442-5054)
Institutions
- Samsung Medical Center (KR)
- Kangbuk Samsung Hospital (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Anticancer Research
- Published
- 2024-09-30
- DOI
- https://doi.org/10.21873/anticanres.17268
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea
- Samsung