Sparing Effect on Cell Survival Under Normoxia Using Ultra-high Dose Rate Proton Beams from a Compact Superconducting AVF Cyclotron
The sparing effect on cell survival was first observed under normoxic conditions for tumor and normal cells with doses exceeding 20 Gy, using proton irradiation at 250 Gy/s extracted from a superconducting AVF cyclotron. This study marks a significant milestone in advancing our understanding of the underlying mechanism behind the sparing effect.
Authors
- Masashi Yagi (ORCID: https://orcid.org/0000-0002-2827-5407)
- Kazuki Fujita (ORCID: https://orcid.org/0000-0003-0332-5831)
- Nagaaki Kamiguchi
- Kazumasa Minami (ORCID: https://orcid.org/0000-0002-3864-6478)
- Kenzo Sasai
- Daizo Amano
- Shinichi Shimizu (ORCID: https://orcid.org/0000-0003-3143-0479)
- Kazuhiko Ogawa (ORCID: https://orcid.org/0000-0001-8872-7690)
- Ryo Hidani
- Shinji Nomura
- K. Nagata
Institutions
- Sumitomo Heavy Industries (Japan) (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2024-09-30
- DOI
- https://doi.org/10.21873/anticanres.17255
- Primary Topic
- Nuclear Physics and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00