Inhaled corticosteroid delivery is markedly affected by breathing pattern and valved holding chamber model
Fluticasone delivery is markedly affected by breathing pattern and VHC model. The observed differences in throat deposition and FPD delivered may have significant clinical implications for side effects and controlling airway inflammation. All VHCs intended for paediatric use should undergo testing using internationally recognised standardised methods incorporating clinically relevant paediatric breathing patterns.
Authors
- Péter Csonka (ORCID: https://orcid.org/0000-0003-0819-7875)
- Lauri Lehtimäki (ORCID: https://orcid.org/0000-0003-1586-4998)
- Laura Ojanperä
- Heini Huhtala
Institutions
- Tampere University (FI)
- Tampere University Hospital (FI)
- Tampere University (FI)
Publication Details
- Journal
- Pediatric Pulmonology
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1002/ppul.27300
- Citations
- 4
- Primary Topic
- Inhalation and Respiratory Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- Suomen Lääketieteen Säätiö
- Tampereen Tuberkuloosisäätiö
- Hengityssairauksien Tutkimussäätiö
- Väinö ja Laina Kiven Säätiö
- Tampereen Lastenklinikan Tuki Ry