Comparing the diagnostic value of targeted with metagenomic next-generation sequencing in immunocompromised patients with lower respiratory tract infection
In summary, our study demonstrated that tNGS offers promising clinical diagnostic accuracy in immunocompromised patients, as evidenced by its favorable comparison with CMT, the composite reference standard, and mNGS.
Authors
- Muyun Wei (ORCID: https://orcid.org/0000-0002-5179-7676)
- Shuangshuang Li (ORCID: https://orcid.org/0000-0001-5887-2280)
- Dejian Gu
- Xinhua Lu (ORCID: https://orcid.org/0000-0001-9120-0013)
- Min Li (ORCID: https://orcid.org/0000-0003-4386-3992)
- Shaowei Mao
- Shengjie Bai
- Kangyi Gu
Institutions
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
- Shanghai Children's Medical Center (CN)
- Annoroad Gene Technology (China) (CN)
Publication Details
- Journal
- Annals of Clinical Microbiology and Antimicrobials
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1186/s12941-024-00749-5
- Citations
- 18
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 6.96
Funders
- Science and Technology Commission of Shanghai Municipality
- National Key Research and Development Program of China