Determining The Relationship Between Diet Inflammatory Index Score, Depression and Chronotype In Individuals with Metabolic Syndrome: An Example of a Training and Research Hospital

Aim: This study aimed to examine the relationship between the depression, chronotype and Dietary Inflammatory Index score in individuals diagnosed with metabolic syndrome. Material and Methods: This study included 100 individuals with metabolic syndrome. The Depression-Anxiety Stress Scale was utilized to assess the depression, stress, and anxiety levels of the participants. Chronotypes were determined using the Morningness-Eveningness Questionnaire, and the Dietary Inflammatory Index (DII) was calculated based on a three-day food consumption record. Results: Of the participants, 53% were women and 47% were men. The depression (10.64±3.91), anxiety (10.38±3.51), and stress (13.12±3.89) scores were significantly higher in the "evening type" group. Female participants had significantly higher depression scores (9.68±4.39) compared to male participants (8.00±3.35) (p=0.033). Analysis of the Dietary Inflammatory Index (DII) scores revealed that women had a more pro-inflammatory diet (3.23±5.69). Additionally, a positive correlation was observed between depression scores and carbohydrate consumption (r=0.264, p=0.002), while a negative correlation was found with the percentage of protein intake (r=-0.336, p=0.001). Conclusion: The study revealed that the majority of individuals with metabolic syndrome exhibit an evening chronotype and are at increased risk for depression, anxiety, and stress. Additionally, it was found that these individuals tend to follow a pro-inflammatory diet. Therefore, it is recommended that the treatment of individuals with metabolic syndrome includes the assessment of their chronotypes, nutritional habits, and psychological states.