A comparative study of the healing effects of sesame oil and TiO2 nanoparticles gel on second-degree burn

Burns, a severe form of soft tissue injury, can cause significant damage and, in extreme cases, be fatal. They also lead to considerable mental and emotional distress due to excessive scarring and skin contractures. Despite various treatment methods, burn care remains a challenging medical issue. In this study, titanium dioxide (TiO2) nanoparticles were synthesized and characterized using Field Emission Scanning Electron Microscopy (FE-SEM), revealing particle sizes ranging from 31.52 to 69.08 nanometers. The impact of biosynthetic nanomaterials and sesame seed oil on burn healing in laboratory rats was investigated. The study compared the effects of a 1% TiO2 solution and 20% sesame oil on burned skin with a control group of rats having natural skin. Fifteen rats were divided into three groups, each receiving daily treatment for 28 days. The results indicated that the TiO2 treatment significantly accelerated healing compared to the sesame seed oil group, which had a slower healing rate of 0.12 points per day. The TiO2 treatment demonstrated a marked improvement in healing speed and effectiveness.