Acute exposure to mercury drives changes in gene expression in Drosophila melanogaster

We found 119 genes with higher gene expression following treatment (including all 5 Drosophila metallothionine genes and a number of heat shock protein genes), and 31 with lower expression (several of which are involved in egg formation). Our results highlight biological processes and genetic pathways impacted by exposure to this toxic metal, and provide motivation for future studies to understand the genetic basis of response to mercury.

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Publication Details

Journal
BMC Research Notes
Published
2024-09-30
DOI
https://doi.org/10.1186/s13104-024-06945-y
Citations
1
Primary Topic
Physiological and biochemical adaptations
Type
article
Field-Weighted Citation Impact
0.46

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article

Acute exposure to mercury drives changes in gene expression in Drosophila melanogaster

Brian J. Sanderson, Dylan J. Sims‐West, Stuart J. Macdonald
1 citations
BMC Research Notes
Physiological and biochemical adaptations
0.46
article

Acute exposure to mercury drives changes in gene expression in Drosophila melanogaster

Brian J. Sanderson, Dylan J. Sims‐West, Stuart J. Macdonald
article en
1 citations

Abstract

We found 119 genes with higher gene expression following treatment (including all 5 Drosophila metallothionine genes and a number of heat shock protein genes), and 31 with lower expression (several of which are involved in egg formation). Our results highlight biological processes and genetic pathways impacted by exposure to this toxic metal, and provide motivation for future studies to understand the genetic basis of response to mercury.

BMC Research NotesVol. 17(1)
University of Kansas (US), Syracuse University (US)
National Institutes of Health
Openalex Percentile: Top 29%
Physiological and biochemical adaptations
0.46
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