Assessment of whole cartilage surface damage in an osteoarthritis rat model: The Cartilage Roughness Score (CRS) utilizing microcomputed tomography
The CRS analysis method emerges as a robust tool for cartilage surface damage assessment. This study demonstrates the potential of automatic 3D analysis over the traditional 2D histological approach when evaluating cartilage surface damage.
Authors
- Patrick Weber (ORCID: https://orcid.org/0000-0003-3626-000X)
- Marina V. Fonti (ORCID: https://orcid.org/0000-0002-2415-8019)
- Marcy Zenobi‐Wong (ORCID: https://orcid.org/0000-0002-8522-9909)
- Mikko Finnilä (ORCID: https://orcid.org/0000-0002-3348-5759)
- Shipin Zhang (ORCID: https://orcid.org/0000-0001-8421-7108)
- Ville‐Pauli Karjalainen (ORCID: https://orcid.org/0000-0001-8376-2454)
- Sami Kauppinen (ORCID: https://orcid.org/0000-0002-4270-2225)
- Vesa Virtanen (ORCID: https://orcid.org/0000-0002-5797-5365)
- Tuomas Frondelius
- David Fercher (ORCID: https://orcid.org/0009-0000-8934-9441)
- Simo Saarakkala (ORCID: https://orcid.org/0000-0003-2850-5484)
- Gonçalo Barreto (ORCID: https://orcid.org/0000-0003-4444-9208)
- Lucia Baixauli-Marin
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
- ETH Zurich (CH)
- University of Oulu (FI)
Publication Details
- Journal
- Osteoarthritis and Cartilage
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1016/j.joca.2024.09.008
- Citations
- 7
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.29
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Academy of Finland