Isolation of the Secondary Building Unit of a 3D Metal–Organic Framework through Clip-Off Chemistry, and Its Reuse To Synthesize New Frameworks by Dynamic Covalent Chemistry
Herein, we present a novel methodology for synthesizing metal clusters or secondary building units (SBUs) that are subsequently employed to construct innovative metal-organic frameworks (MOFs) via dynamic covalent chemistry. Our approach entails extraction of SBUs from preformed MOFs through complete disassembly by clip-off chemistry. The initial MOF precursor is designed to incorporate the desired SBU, connected exclusively by cleavable linkers (in this study, with olefinic bonds). Cleavage of all the organic linkers (in this study, via ozonolysis under reductive conditions) liberates the SBUs functionalized with aldehyde groups. Once synthesized, these SBUs can be further reacted with amines in dynamic covalent chemistry to build new, rationally designed MOFs.
Authors
- Inhar Imaz (ORCID: https://orcid.org/0000-0002-0278-1141)
- Judith Juanhuix (ORCID: https://orcid.org/0000-0003-3728-8215)
- Jorge Albalad (ORCID: https://orcid.org/0000-0001-5850-6723)
- Dongsik Nam (ORCID: https://orcid.org/0000-0002-9941-3504)
- Yunhui Yang (ORCID: https://orcid.org/0000-0002-6007-2335)
- Roberto Sánchez‐Naya (ORCID: https://orcid.org/0000-0001-7145-266X)
- Daniel Maspoch (ORCID: https://orcid.org/0000-0003-1325-9161)
- Sara Ruiz‐Relaño
- Alba Cortés‐Martínez
Institutions
- Institució Catalana de Recerca i Estudis Avançats (ES)
- Universitat Autònoma de Barcelona (ES)
- ALBA Synchrotron (Spain) (ES)
- Institut Català de Nanociència i Nanotecnologia (ES)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1021/jacs.4c09077
- Citations
- 16
- Primary Topic
- Metal-Organic Frameworks: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.54
Funders
- Ministerio de Ciencia, Innovación y Universidades
- Centres de Recerca de Catalunya
- Institut Català de Nanociència i Nanotecnologia
- European Commission
- Generalitat de Catalunya
- China Scholarship Council
- Ministerio de Ciencia e Innovación
- Agència de Gestió d'Ajuts Universitaris i de Recerca
- European Regional Development Fund
- Agencia Estatal de Investigación
- H2020 European Research Council