Comparative evaluation of cigarette smoke and a heated tobacco product on microglial toxicity, oxidative stress and inflammatory response
These results highlight the differential toxicological profile of cigarette smoke and HTP on microglial cells, suggesting a potential harm reduction strategy for neurodegenerative disease for smokers unwilling or unable to quit.
Authors
- Alfio Distefano (ORCID: https://orcid.org/0000-0003-3323-9344)
- Angela Maria Amorini (ORCID: https://orcid.org/0000-0003-3525-9955)
- Rosalia Emma (ORCID: https://orcid.org/0000-0002-2564-553X)
- Massimo Caruso (ORCID: https://orcid.org/0000-0002-4412-2080)
- Simona Denaro (ORCID: https://orcid.org/0000-0003-1910-0573)
- Nunzio Vicario (ORCID: https://orcid.org/0000-0001-5934-3962)
- Antonio Giordano (ORCID: https://orcid.org/0000-0002-5959-016X)
- Giovanni Li Volti (ORCID: https://orcid.org/0000-0002-8678-2183)
- Barbara Tomasello (ORCID: https://orcid.org/0000-0001-6049-942X)
- Amer M. Alanazi (ORCID: https://orcid.org/0000-0003-4172-8973)
- Lucia Longhitano (ORCID: https://orcid.org/0000-0002-1296-5884)
- Ang Sun (ORCID: https://orcid.org/0000-0002-8644-0407)
- Konstantinos Partsinevelos
- Laura Orlando (ORCID: https://orcid.org/0000-0001-6201-0157)
Institutions
- King Saud University (SA)
- University of Catania (IT)
- Temple University (US)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1186/s12967-024-05688-5
- Citations
- 16
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 3.74
Funders
- King Saud University
- Università di Catania