Impact of Different Packaging Configurations on A Topical Cream Product
Different methods of dispensing topical semisolid products can result in metamorphosis and Q3 changes that may have the potential to alter the bioavailability of an active ingredient. These findings have potential implications for product developers and regulators, related to the manufacturing and comparative testing of reference standard and prospective generic products dispensed from different packaging configurations.
Authors
- Yousuf Mohammed (ORCID: https://orcid.org/0000-0002-7825-7557)
- Jeffrey E. Grice (ORCID: https://orcid.org/0000-0002-8862-4461)
- Elena Rantou
- Krishna Chaitanya Telaprolu (ORCID: https://orcid.org/0000-0002-3439-7152)
- Maike Windbergs (ORCID: https://orcid.org/0000-0001-9475-699X)
- Jason R. Stokes (ORCID: https://orcid.org/0000-0001-7784-9297)
- Heather M. Shewan (ORCID: https://orcid.org/0000-0002-4405-679X)
- Michael S. Roberts (ORCID: https://orcid.org/0000-0003-3894-5301)
- Heather A. E. Benson (ORCID: https://orcid.org/0000-0002-1818-5627)
- Sam G. Raney (ORCID: https://orcid.org/0000-0003-3562-8175)
- Nicole Jung (ORCID: https://orcid.org/0000-0001-9513-2468)
- S. N. Namjoshi
Institutions
- Goethe University Frankfurt (DE)
- United States Food and Drug Administration (US)
- Center for Drug Evaluation and Research (US)
- The University of Queensland (AU)
- Curtin University (AU)
- Basil Hetzel Institute (AU)
- The University of Adelaide (AU)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1007/s11095-024-03772-5
- Citations
- 6
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.25
Funders
- University of Queensland
- U.S. Food and Drug Administration