Clinical and epidemiological characteristics of amyotrophic lateral sclerosis in an Egyptian cohort

Our cohort was characterized by a younger age of onset, male predominance, more familial cases, within average Initial ALSFRS-R scores as well as diagnostic delay. Juvenile ALS patients were much more common in our population. These findings suggest an influential presence of genetic and epigenetic factors affecting the clinical phenotype of Egyptian ALS patients.

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Publication Details

Journal
Neurological Sciences
Published
2024-09-30
DOI
https://doi.org/10.1007/s10072-024-07760-w
Citations
4
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
1.48

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article

Clinical and epidemiological characteristics of amyotrophic lateral sclerosis in an Egyptian cohort

Kareem Omran, Radwa Soliman, Nagia Fahmy, Enass Onbool
4 citations
Neurological Sciences
Amyotrophic Lateral Sclerosis Research
1.48
article

Clinical and epidemiological characteristics of amyotrophic lateral sclerosis in an Egyptian cohort

Kareem Omran, Radwa Soliman, Nagia Fahmy, Enass Onbool
article en
4 citations

Abstract

Our cohort was characterized by a younger age of onset, male predominance, more familial cases, within average Initial ALSFRS-R scores as well as diagnostic delay. Juvenile ALS patients were much more common in our population. These findings suggest an influential presence of genetic and epigenetic factors affecting the clinical phenotype of Egyptian ALS patients.

Neurological SciencesVol. 46(3)
Ain Shams University (EG)
Ain Shams University
Good health and well-being
Openalex Percentile: Top 17%
Amyotrophic Lateral Sclerosis Research
1.48
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