ER–mitochondria contact sites regulate hepatic lipogenesis via Ip3r-Grp75-Vdac complex recruiting Seipin
The findings of this study provide a new insight into the regulatory role of MERCS-recruited SEIPIN in hepatic lipid synthesis via Ip3r-Grp75-Vdac complex-mediated Ca<sup>2+</sup> signaling, highlighting the critical contribution of MERCS in hepatic lipid homeostasis.
Authors
- Zhen-Yu Bai
- Yu–Feng Song
- Y. Chi
- Guang‐Li Feng
- Xiao‐Hong Lai
Institutions
- Huazhong Agricultural University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1186/s12964-024-01829-x
- Citations
- 19
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 4.44