In vivo edited eosinophils reconcile antigen specific Th2 response and mitigate airway allergy
We constructed Cedit, which could edit eosinophils into Meos in vivo. Meos could induce antigen specific CD4<sup>+</sup> T cell apoptosis, and reconcile airway Th2 polarization.
Authors
- Xiang‐Qian Luo (ORCID: https://orcid.org/0000-0001-5132-0512)
- Jianwen Zhong
- Qinmiao Huang
- Yuanyi Zhang (ORCID: https://orcid.org/0000-0002-2609-5672)
- Jinna Yang
- Gui Yang
- Pingchang Yang (ORCID: https://orcid.org/0000-0002-4857-7568)
- Yü Liu (ORCID: https://orcid.org/0000-0003-2211-3535)
- Li‐Hua Mo
- Gaohui Wu (ORCID: https://orcid.org/0000-0002-2839-3112)
- Haoyue Zheng
Institutions
- Shenzhen University (CN)
- Longgang Central Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Shenzhen Third People’s Hospital (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1186/s12964-024-01824-2
- Citations
- 3
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.98