Gram-Negative Colonization and Bacterial Translocation Drive Neonatal Sepsis in the Indian Setting
Neonates with sepsis exhibited significant gut microbiome dysbiosis, characterized by increased Proteobacteria and reduced beneficial bacteria diversity. These findings highlight the potential of microbiome profiling as a diagnostic tool and underscore the importance of gut microbiota modulation in managing neonatal sepsis.
Authors
- Leslie Lewis (ORCID: https://orcid.org/0000-0002-3467-6821)
- Jayashree Purkayastha (ORCID: https://orcid.org/0000-0002-9754-1756)
- Padmaja A. Shenoy (ORCID: https://orcid.org/0000-0001-6781-5579)
- Apurv Barche (ORCID: https://orcid.org/0000-0001-7821-1762)
- Faiza Iqbal (ORCID: https://orcid.org/0000-0002-1335-1796)
- K.E. Vandana
Institutions
- UMass Memorial Health Care (US)
- Manipal Academy of Higher Education (IN)
- UMass Memorial Medical Center (US)
Publication Details
- Journal
- Journal of Epidemiology and Global Health
- Published
- 2024-09-30
- DOI
- https://doi.org/10.1007/s44197-024-00303-8
- Citations
- 5
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Kasturba Medical College, Manipal