Development of an intraventricular Adeno-Associated Virus-based labelling strategy for glioblastoma cells nested in the subventricular zone
This study not only sheds light on the putative outcome of SVZ-nested GBM cells but also shows that icv injection of rAAV vectors allows to transduce and potentially modulate gene expression in hard-to-reach GBM cells of the periventricular area.
Authors
- Gilles Reuter (ORCID: https://orcid.org/0000-0002-7484-3110)
- Emmanuel Di Valentin (ORCID: https://orcid.org/0000-0002-5287-7950)
- Bernard Rogister (ORCID: https://orcid.org/0000-0003-1754-6002)
- Virginie Neirinckx (ORCID: https://orcid.org/0000-0002-9050-6579)
- Damla Isci (ORCID: https://orcid.org/0000-0002-9388-7936)
- Alexandre Hego (ORCID: https://orcid.org/0009-0007-7968-6795)
- Didier Martin (ORCID: https://orcid.org/0000-0001-7325-4958)
- Arnaud Lombard (ORCID: https://orcid.org/0000-0002-7789-0801)
Institutions
- University of Liège (BE)
- Centre hospitalier régional de la Citadelle (BE)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1093/noajnl/vdae161
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fonds De La Recherche Scientifique - FNRS
- Université de Liège